Speaker
Description
MXCuBE goes serial
M.Oskarsson, A.Beteva, D. de Sanctis, S.Basu, J. Orlans, S.Rose, S. Debionne, A. Homs, J. Kieffer, J.Meyer
The ESRF Extremely Brilliant Source upgrade programme included the construction of the new ID29 beamline, the first in the world beamline fully dedicated to room-temperature experiments and time-resolved macromolecular serial crystallography. The beamline presents a new layout in terms of design, and the experimental setup was designed to fully benefit from the characteristics of the EBS machine. The primary objective is to collect diffraction data from micrometer sized crystalline samples at room temperature with a microsecond time resolution. The beamline presents a flexible sample environment that can accommodate fixed target, viscous injectors, microfluidics or tape drives. The experimental setup is completed with a Jungfrau 4M detector that has been integrated in the ESRF data acquisition pipeline and can be operated at high data acquisition rates.
MXCuBE, the state-of-the-art experiment control software used at all ESRF MX beamlines, for remote, high-throughput attended and unattended data collections, was expanded with new Serial Macromolecular Crystallography features for ID29. Several new scanning functions have been introduced to perform microsecond data acquisitions on Silicon chips, foils, jets, and tape drive experiments. Additionally, the implementation of newly developed or prototyped chips can be easily added. A custom dialog has been developed within MXCuBE for the chips so that the user can easily select which parts of the chip to scan. The PSI Jungfrau 4M detector is controlled through Bliss and the latest version of the LImA2 library, which integrates an automatic hit-finding algorithm and optional online frame rejection and compression.
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