Speaker
Description
The FMX (Frontier Microfocusing Macromolecular Crystallography) beamline at the NSLS-II light source has been developing a new experimental station for fixed target time-resolved serial crystallography on biological systems. We present here the controls-system for a chip scanner to enable the rapid collection of large numbers of room temperature crystallographic measurements on biological samples. In addition to static measurements, samples can be excited in a pump-probe scheme by the injection of compounds suspended in liquid through a microdrop dispensing system, at timed intervals preceding the measurement. Enabling this has required the implementation of a full stack integrated solution, involving direct programming of the powerPMAC motion controller, control of motion, triggering and detectors through EPICS, data collection through Ophyd/Bluesky, and the implementation of an optional GUI for control of the experiment. Here, I will outline the components involved in this process, as well as the successes and pitfalls which we have encountered during the implementation and testing of the scanner, and show the results from the first experiments at the beamline.
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