New advances in Fragment Screening, AI and Cryo-EM are rapidly transforming the field of structure-based drug discovery. EMBL, ESRF and Instruct-ERIC with sponsorship from the EC-funded Fragment Screen project (GA-ID: 101094131) are organising a workshop on Advances in Fragment Screening and Structure-Based Drug Discovery on January 28th and 29th, 2027 at the EPN Campus in Grenoble, France.
Marking the end of the EC-funded Fragment-Screen project, focusing on technology development for fragment screening and drug discovery, the EMBL and ESRF Joint Structural Biology and Imaging Group (JSBIG) and the Fragment-Screen consortium will host a 1.5-day symposium.
This workshop will convene representatives from academia, industry and facilities across Europe and beyond to discuss recent advances in structure-based drug design. Topics will include new technologies X-ray and NMR-based fragment screening, AI and Cryo-EM in drug design among others, as well as access opportunities at academic facilities.

Scientific contributions
We welcome poster presentations from participants, some of which will be selected for oral presentation. Abstract submission via: https://survey.esrf.fr/index.php/141582?lang=en
Accommodation
Accommodation at the EPN Campus Guesthouse (free of charge) is available for a limited number of Early career-participants. Please indicate in your registration if you wish to benefit from this possibility - we will reconfirm availability individually but please note that preference will be given to PhD students that submitted an abstract for a poster or a talk.
For other participants, some hotel options are mentioned in the registration.
Confirmed speakers:
Stephen Fesik, Vanderbilt University, USA
Antje Gohla, University of Würzburg, Germany
Jose A. Marquez, EMBL, France
Filipe Menezes, Helmholtz Munich, Germany
Didier Nurizzo, ESRF, France
Modesto Orozco, IRB, Barcelona, Spain
Harald Schwalbe, Goethe-University, Frankfurt
Irina Cornaciu, ALPX s.s.s
Registration deadline: Thursday 26 November 2026
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